Papel del linezolid en el tratamiento de endocarditis / No disponible

No disponible

Paciente con osteomielitis crónica que desarrolla caquexia / Patient with chronic osteomyelitis who developed cachexia

No disponible

[The aggressive clinical course of pneumococcal endocarditis]. / El curso clínico agresivo de la endocarditis neumocócica.

The aggressive clinical course of pneumococcal endocarditis. A retrospective study was conducted between 2000 and 2005 in five patients with pneumococcal endocarditis were diagnosed at our center. Three female and 2 males, 13 to 76 year-old, were attended. Most of them had left valve endocarditis and were suffering from predisposing conditions. All of them developed distant complications as embolism or septic metastases. Two patients were successfully operated. Surgery was considered in another one but it was discarded due to her poor general condition. This was the only death in the series.

El curso clínico agresivo de la endocarditis neumocócica / The aggressive clinical course of pneumococcal endocarditis

Realizamos un estudio retrospectivo de cinco casos diagnosticados de endocarditis neumocócica en nuestro hospital entre 2000 y 2005. Se trata de tres mujeres y dos varones con edades entre 13 y 76 años. La mayoría tuvieron afectadas las válvulas izquierdas y presentaron enfermedades predisponentes. Todos los pacientes presentaron enfermedad neumocócica a distancia en forma de embolismo o metástasis séptica. En dos pacientes se llevó a cabo cirugía cardíaca con éxito y en otro se desestimó por la mala situación clínica, siendo el único caso que falleció (AU)

A retrospective study was conducted between 2000 and 2005 in five patients with pneumococcal endocarditis were diagnosed at our center. Three female and 2 males, 13 to 76 year-old, were attended. Most of them had left valve endocarditis and were suffering from predisposing conditions. All of them developed distant complications as embolism or septic metastases. Two patients were successfully operated. Surgery was considered in another one but it was discarded due to her poor general condition. This was the only death in the series (AU)

[Expert recommendations for the diagnosis and treatment of chronic hepatitis C infection in the prison setting]. / Recomendaciones de expertos sobre el diagnóstico y tratamiento de la hepatitis C crónica en el medio penitenciario.

The prevalence of HCV infection in Spanish prisons is very high (38.5%). The characteristics of the infected patients, particularly the high rate of HIV coinfection, makes it very likely that the morbidity and mortality produced by serious liver disease secondary to this infection will increase considerably in the coming years. A group of Spanish experts with experience in patients who are inmates has been invited to establish a series of recommendations for the diagnosis and treatment of chronic hepatitis C infection in Spanish prisons.

Recomendaciones de expertos sobre el diagnóstico y tratamiento de la hepatitis C crónica en el medio penitenciario / Expert recommendations for the diagnosis and treatment of chronic hepatitis C infection in the prison setting

La prevalencia de la infección por el virus de la hepatitis C (VHC) en las prisiones españolas es muy elevada (38,5%). Las características de los pacientes infectados, especialmente la elevada coinfección con el virus de la inmunodeficiencia humana (VIH), hacen probable que la morbilidad y mortalidad producida por enfermedad hepática grave secundaria a esta infección aumente de forma considerable en los próximos años. Un grupo de expertos multidisciplinar con experiencia con pacientes internados en prisiones españolas ha sido invitado a establecer una serie de recomendaciones para el diagnóstico y tratamiento de la hepatitis C en las prisiones españolas

The prevalence of HCV infection in Spanish prisons is very high (38.5%). The characteristics of the infected patients, particularly the high rate of HIV coinfection, makes it very likely that the morbidity and mortality produced by serious liver disease secondary to this infection will increase considerably in the coming years. A group of Spanish experts with experience in patients who are inmates has been invited to establish a series of recommendations for the diagnosis and treatment of chronic hepatitis C infection in Spanish prisons

[Bilateral papilloedema as the initial symptom of POEMS syndrome]. / Edema de papila bilateral como manifestación inicial de un síndrome de POEMS.

INTRODUCTION: Oedema of the papilla, or papilloedema, is usually due to intracranial hypertension, but can sometimes be the initial symptom of systemic diseases like Guillain-Barre syndrome, neurosarcoidosis, Leber's disease, Lyme disease or POEMS syndrome, among others. We report on a case that occurred at the Hospital General Universitario in Alicante, in which papilloedema was the initial symptom of POEMS syndrome. CASE REPORT: A 36-year-old female, with no relevant past history, who visited after suffering a left-side frontal oppressive headache for five days; onset was sudden, there was no concomitant nausea or vomiting, it did not get worse when Valsalva manoeuvres were performed and there were no other accompanying symptoms. The examination revealed nasal blurring in the visual field of the right eye and papilloedema in the left eye, hyperpigmentation of the skin on the face and upper chest area that respected creases in the skin, painful distal tactile hypaesthesia in the lower limbs and bilateral areflexia of Achilles' tendons and patellar hyperreflexia. After conducting a number of different complementary tests intracranial space-occupying lesions and intracranial hypotension were both ruled out and the patient was diagnosed with mixed-type sensory-motor chronic polyneuropathy in the upper limbs, and in the lower extremities with predominantly distal involvement, bilateral oedema of the papilla and skin photosensitivity. Two years later the patient had hepatomegaly, subclinical hypothyroidism and sclerodermiform alterations of the skin, which suggested a probable diagnosis of POEMS syndrome that was later confirmed by the presence of monoclonal component in blood and urine. CONCLUSIONS: Papilloedema is rarely seen as the initial symptom of POEMS syndrome, but it must be included in the differential diagnosis of this pathology due to the diagnostic and therapeutic implications it entails.